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Professors

Lian Yu

发布者:系统管理员发布时间:2009-10-01浏览次数:2693

YU Lian

 

Department of Veterinary Medicine

Professor of Immunology

 

Phone & Fax: 86-571-8697 1894

E-mail: yulian@zju.edu.cn

Address:

256# Animal Science Building

Zhejiang University

268 Kaixuan Road

Hangzhou, Zhejiang 310029

P. R. CHINA

 

Research Interests:

1. Molecular immunology, especially cytokines

2. Viral pathogenesis of infectious diseases of avian, especially immunosuppressive virus

 

Education and Visiting Fellow:

BVS: Zhejiang Agricultural University, Hangzhou, China, 1961-1965

Visiting professor: Tokyo University, Hokkaido University, Gifu University, 1990

 

Academic Positions

Associate director, Zhejiang Society of Immunology

Member, Chinese Society of Immunology

 

Patents and awards

[1]     Yu Lian, Li Jianrong, Huang Yaowei, Li long. Polyprotein gene vaccine of Infectious Bursal Disease Virus. Patent No.C12N15/33.

[2]     Yu Lian, Zhang Yaozhou, Song Kunhua, Jin Yongfeng, Huang Yaowei. Production of VP2 subunit vaccine of Infectious Bursal Disease Virus. Patent No. ZL00105777.4.

[3]     Yu Lian, Li Jianrong, Huang Yaowei, Fang Yongjun. Molecular adjuvant of chicken interleukin 2 gene. Patent application No. 021039789.8.

[4]     Yu Lian, Li long, Wei Yongwei. Construction and attenuation of recombinant infectious bursal disease virus. Patent application No. 200510061550.5.

[5]     Yu Lian, Li Jianrong, Huang Yaowei, Fang Weihuan, Zhou Jiyong, Lu Mijia, Xie Ronghui, Fan Yongjun, Li Long. Study on gene immunization of infectious bursal disease virus. The first-class award for science and technology of Zhejiang province, 2002.

[6]     Yu Lian, Song Kunhua, Zhou Jiyong, Yu Xuping, Li Shuangmao. The study on expression of major host protective antigen VP2 of infectious bursal disease virus and the immunogenicity of its product The second-class award for science and technology of Zhejiang province, 2000.

 

Recent Publications:

[1]      Li Long, Fang Weihuan, Li Jianrong, Fang Li, Huang Yaowei, Yu Lian, 2006. Oral DNA vaccination with the polyprotein gene of infectious bursal disease virus (IBDV) delivered by attenuated Salmonella typhimurium elicits protective immune responses in chickens. Vaccine, in press.

[2]     Zhenqiang You, Lian Yu, Chaozheng Zhang, Long Li, Mijia Lu, Zhijuan Mao, Yan Liu, Wuying Chu, 2006. Distribution and expression of recombinant plasmid encoding chicken interleukin-2. Veterinary research communications, in press.

[3]     Yan Liu, Lian Yu, Xiu-yang Guo, Ting-qing Guo, Sheng-peng Wang, Chang-de Lu, 2006. Analysis of tissue-specific region in sericin 1 gene promoter of Bombyx mori. Biochemical and Biophysical Research Communications, 342(1), 273-279.

[4]     Tong-le Deng, Lian Yu, Ya-kun Ge, Le Zhang and Xiao-xiang Zheng, 2005. Intracellular-free calcium dynamics and F-actin alteration in the formation of macrophage foam cells. Biochemical and Biophysical Research Communications, 338(2), 748-756.

[5]     Xu Jian, Deng Tongle, Li Long, You Zhenqiang, Wan Wang-Jun, Yu Lian, 2005. The nitric oxide inducing function and intracellular movement of chicken interleukin 18 in cell culture. Acta Biochim Biophys Sin, 37(10), 688¨C693.

[6]     Li Long, Huang Yaowei, Wang Liansheng, Wan Wangjun, Yu Lian, 2005. Synthesis of reassortant infectious bursal disease virus in chickens injected directly with infectious clones from different virus strains. Acta Biochim Biophys Sin, 37(3), 192-198.

[7]     Jianrong Li, Xueya Liang, Yaowei Huang, Songshu Meng, Ronghui Xie, Ruitang Deng, Lian Yu, 2004. Enhancement of the immunogenicity of DNA vaccine against infectious bursal disease virus by co-delivery with plasmid encoding chicken interleukin 2. Virology, 329(1), 89-100

[8]     Li Jianrong, Huang Yaowei, Liang Xueya, Lu Mijia, Li long, Yu Lian, Deng Ruitang, 2003. Plasmid DNA encoding antigens of infectious bursal disease viruses induced protective immune responses in chickens: factors influencing efficacy. Virus Research, 98(1), 63-74.

[9]     Huang Yaowei, Li Long, Li Jianrong, Yu Lian, 2003. Rapid construction of infectious clones of infectious bursal disease virus. Acta Biochim Biophys Sin, 35(4), 338-344.

[10] Lian Yu, Jianrong Li, Yaowei Huang, Ruitang Deng, 2001. Molecular characteristics of full-length of genomic segment A of three infectious bursal disease viruses in China: two attenuated strains and one virulent field strain. Avian Diseases, 45(4), 862-874.

[11] Huang Yaowei, Yu Lian, Ding Hongmei, Li Jianrong, Song Kunhua, 2001. Amplification and cloning by long rt-pcr of full-length genome of larger segment of chicken infectious bursal disease virus. Acta Biochim Biophys Sin, 33(3), 355-359.

[12] Li Jianrong, Huang Yaowei, Meng Songshu, Liang Xueya, Xie Ronghui, Yu Lian, 2001. Cloning and phylogenetic analysis of interleukin-2 gene in xiaoshan chicken, a chinese local chicken breed. Acta Biochim Biophys Sin, 33(6), 713-718.

[13] Lian Yu, Konghua Song, Yaozhou Zhang, Ruitang Deng, 2000. Cloning and expression of the VP2 gene of an infectious bursal disease virus. Avian Disease, 44, 170-178.

[14] Song kunhua, Jin Yongfeng, Huang Yaowei, Zhang Yaozhou, Yu lian, 2000. Infectious bursal disease virus structural protein VP2 expressed by a baculovirus recombinant in bombyx mori. Acta Biochim Biophys Sin, 32 (3), 281-284.

 

 
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